Breaking Open the Black Box of Pregnancy Loss
Approximately 60% of pregnancies are lost before 6 weeks of pregnancy. Our group investigates the role of the placenta in why some pregnancies fail to properly communicate with the uterus, preventing embryo implantation and invasion and causing miscarriage. Beyond miscarriages, improper placental invasion can compromise placental development and function, putting both mother and baby at risk of pre-eclampsia and intrauterine growth restriction.
The West Lab for Placental Biology uses cutting-edge technologies and an interdisciplinary approach to identify the mechanisms that drive improper placental signaling and prevent embryo implantation and invasion.
Cutting Edge Techniques
We use placental stem cells and animal embryos to recapitulate early placental development. Current techniques include 3D spheroid culture, extended embryo culture, genome editing with Crispr-Cas9, computational biology, and immunofluorescence.
Keep up with us on Twitter!
-
RT @MarcSirard: Finally we have a study to characterize F1 bovine IVF animals from multiple herds Comparison of cattle derived f… https://t.co/CohWa4xCZK -
This was a fantastic preprint. Excited to see the final version in print! https://t.co/Fr4Yebebsd
-
RT @WinRS_SSR: 1/ Today we celebrate the AMAZING Prof Bolden-Tiller @TuskegeeUniv “During Women's History Month, it's a special ti… https://t.co/fn4tS5hVjI
-
My undergrads have started the "how old were you when this song came out then dying laughing when I tell them the a… https://t.co/1yRrWYIJ4u
-
-
RT @SamanthaLWilson: I have funded MSc/PhDs available in my lab. Please contact me if you are interested in computational bio, genomics,… https://t.co/g2FBmMLXBE
-
RT @suehammoud1: Hi Everyone, My lab is recruiting a postdoc. If you are interested in testis organiod generation, sperm chromatin,… https://t.co/lCH2Yobd8B
-
RT @TaylorPini: 📢@SSR_Trainees it's time to vote for your next SSR Trainee rep! The ballot is packed with ridiculously amazing cand… https://t.co/YPxBoxqfHP
-
RT @SSRepro: #SSR is NOW accepting applications for the 2023 Burroughs Wellcome Fellowships! Check them out 👇 Trainee Applicati… https://t.co/cCJ9hHpxZR
-
Incredible work! Chromosomal sex conversion, in vitro oocyte generation, eradication of trisomies in vitro. This pa… https://t.co/qTmopj3HOi